Organizations:
http://alternet.org/ -- It’s always nice to hear news that wasn’t sent as a government or corporate press release first!
http://www.prwatch.org/ -- The Center for Media and Democracy will tell you who wrote and sent the press release and more importantly, why! It’s the Matrix’s Red Pill of Media. Read it regularly and you’ll never look at news the same way again. Nor should you. You can’t consider yourself an informed citizen without knowing where your information feeds really come from.
http://www.edge.org/ -- John Brockman’s site for his stable of rock-star academics and their writings
www.hplusart.org – My buddy Russell Rukin’s site, devoted to creatives interested in the H+ future
http://www.transhumanism.org/ -- The site of the World Transhumanist Association. You may not agree with them. But you should at least listen to what they have to say. It may be your future.
http://www.accelerating.org/ -- The Acceleration Studies Foundation, run by another buddy, John Smart

Authors:
http://www.theworksoftimpowers.com/ -- Tim Powers is one of the great contemporary fantasy writers. Read The Anubis Gates and Last Call.
http://www.neilgaiman.com/ -- The Great Gaiman. To know him is to love him. Especially American Gods.
http://www.dansimmons.com/ -- His Hyperion series is among the best SF of all time.
http://trevanian.com/ -- He wrote one of the best espionage novels of all time with Shibumi. May the ever elusive Trevanian rest in peace…
http://techgnosis.com/ -- Culture writer Erik Davis’ site. He connects the cultural dots and spins your head around. In a good way.

Gaming:
http://www.peacemakergame.com/ -- Think you’ve got all the answers? You either play the Israeli PM or the Palestinian President. And then you have to make the hard choices…
http://www.food-force.com/ -- The U.N. game that shows just how hard it is to solve global hunger.

Blogs on Science, Futurism, etc.:
http://www.corante.com/brainwaves/ -- Zach Lynch’s thoughtful ponderings about our neurofuture.
http://foresight.org/nanodot/ -- “The Original Nanotechnology Weblog” from the Foresight Institute
http://www.softmachines.org/wordpress/ -- Richard Jones’ nano-blog
http://nanohype.blogspot.com/ -- David Berube’s (NanoHype) blog